News

Positive data for the Phase 1 trial of PharmaMar’s plitidepsin combined with bortezomib and dexamethasone for the treatment of relapsed and/or refractory multiple myeloma will be presented at the 52nd Congress of the American Society of the Clinical Oncology (ASCO) June 3-7  in Chicago. Dr. María Victoria Mateos, M.D., of the Hematological…

Amgen announced it will present new data on its cancer portfolio at the 21st Congress of the European Hematology (EHA) Association taking place next month in Copenhagen. The data will include recent evaluations of the drugs Blincyto (blinatumomab), Kyprolis (carfilzomib), Aranesp (darbepoetin alfa) and Nplate (romiplostim) in treating a range of malignancies, such as multiple…

Spain-based PharmaMar announced the company will present data from several clinical studies of three of its anti-tumoral compounds of marine origin — plitidepsin, Yondelis (trabectedin), and PM1183 — at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting June 3-7 in Chicago. “The results that we are going to…

Results from an ongoing clinical trial supports the use of upfront autologous stem cell transplantation (ASCT) to treat multiple myeloma patients age 65 or younger. The findings, in a report titled “Upfront autologous stem cell transplantation (ASCT) versus novel agent-based therapy for multiple myeloma (MM): A randomized phase 3 study of…

Genmab has announced positive results from its Phase 3 POLLUX study investigating the efficacy of daratumumab, in combination with lenalidomide and dexamethasone, to treat patients with relapsed or refractory multiple myeloma, compared to lenalidomide and dexamethasone alone. The ongoing trial met its primary endpoint, with treated patients demonstrating improved progression-free survival, indicating that the…

Ajai Chari, MD, director of clinical research in the Multiple Myeloma Program at the Icahn School of Medicine at Mount Sinai in New York, and Navneet Majhail, MD, MS, director of the Blood & Marrow Transplant Program at Cleveland Clinic, recently shared their views and analyses of two studies investigating the role and…

Leisure-time physical activity is associated with a lower risk for many types of cancer, including a 17 percent lower risk for myeloma. These key findings were independent of body size or smoking history, indicating that it is essential to educate inactive adults of the benefits of physical activity, with an emphasis on its influence…

Newton, Massachusetts-based Karyopharm Therapeutics has published the results from its Phase 1 trial of selinexor (KPT-330) in patients with advanced solid tumors in the Journal of Clinical Oncology, revealing clinically significant anti-tumor activity for the drug. These results will serve as a basis for further clinical trials in multiple…

Three organizations — CURE Media Group, Multiple Myeloma Research Foundation (MMRF) and Takeda Oncology — joined together in the Moving Mountains for Multiple Myeloma fundraiser to support multiple myeloma (MM) research. As a recent second event in this program, 12 MM patients, doctors, family members, and caregivers hiked the Bright…

Bristol-Myers Squibb (BMS) Company and AbbVie have announced that the European Commission (EC) has approved Empliciti™ (elotuzumab) for the treatment of multiple myeloma in combination with Revlimid™ (lenalidomide) and dexamethasone for patients hho received prior therapy at least once. The U.S. Food and Drug Administration had already approved…