News

Following a three-year hiatus due to the COVID-19 pandemic, the Patient and Family Seminar hosted by the International Myeloma Foundation (IMF) will return to its in-person format for 2023. The free event, which also may be attended virtually, is slated for March 17-18 in Boca Raton, Florida. It’s…

Extremes in body mass index (BMI) — a ratio of weight to height that’s used to estimate a person’s healthy weight — are associated with a worse prognosis among people with multiple myeloma, according to data from more than 1,000 patients. Specifically, underweight and severely obese patients experienced a…

Huadong Medicine has been granted the exclusive rights in China to commercialize CT053, CARsgen Therapeutics’ investigational cell therapy for people with relapsed or refractory multiple myeloma (RRMM), pending the treatment’s potential approval by regulators in the country. The two companies, both based in China, have entered a…

In people with newly diagnosed multiple myeloma following a stem cell transplant, a triple-combination maintenance therapy — of Revlimid (lenalidomide), Kyprolis (carfilzomib) and dexamethasone — significantly extended the time to disease progression or death, by 49%, compared with Revlimid alone. That’s according to an interim analysis of…

Janssen Pharmaceuticals is seeking European Union approval for talquetamab, a subcutaneous (under-the-skin) antibody therapy for hard-to-treat multiple myeloma. The request, in the form of a marketing authorization application to the European Medicines Agency (EMA), will be reviewed under accelerated assessment, which reduces the expected review period from…

Janssen has submitted an application with the U.S. Food and Drug Administration (FDA) asking that talquetamab be approved to treat relapsed or refractory multiple myeloma. “We look forward to working closely with the FDA in their review of the talquetamab submission,” Peter Lebowitz, MD, PhD, global oncology…

The International Myeloma Foundation (IMF) is one of the nonprofit organizations awarded the 2022 Amazon Web Services (AWS) IMAGINE Grant, which was established to help harness technology for patients’ needs. IMF was a winner in the Momentum to Modernize category, wherein its efforts to use cloud technology to educate…

SP-3164, an investigational small molecule protein degrader, showed potential for improved anti-multiple myeloma activity over similar approved compounds. That’s according to preclinical data from its developer Salarius Pharmaceuticals that showed SP-3164 triggered the death of lab-grown cancer cells and held back cancer growth in a mouse model of…

Caribou Biosciences will soon start testing its new CAR T-cell therapy candidate, CB-011, in people with relapsed or refractory multiple myeloma. A Phase 1 trial will begin enrolling eligible adults in early 2023 at multiple centers, according to the company. The announcement follows clearance of the company’s investigational…

GC012F, Gracell Biotechnologies’ investigational dual FastCAR T-cell therapy, was safe and highly effective at eradicating cancer cells in people with high-risk, newly diagnosed multiple myeloma, according to preliminary findings from an ongoing Phase 1 trial. “We are thrilled to report that BCMA/CD19 dual targeting FasTCAR-T GC012F is showing…