One World Cannabis to Test Mice in Pursuit of Therapies Targeting Multiple Myeloma Cancer Cells

One World Cannabis to Test Mice in Pursuit of Therapies Targeting Multiple Myeloma Cancer Cells

Israel’s One World Cannabis (OWC) says it’s moving forward to mouse models to test its unique formula of cannabinoid-based therapies targeting cancer cells. This decision followed promising results from preclinical in vitro studies.

“After in-depth and extensive review and assessment of the study’s results accumulated so far, OWC’s research committee determined that the medical and scientific accepted multiple myeloma mice model is the best way to progress, compared to other possible known scientific paths,” Yehuda Baruch, OWC’s chief science officer and director of research and regulatory affairs. said in a press release.

Future studies will focus on determining the most effective dosages and suitable delivery systems. OWC expects to finish trials on mouse models by this fall, said Baruch, adding that “this unique study, which we designed to pursue and secure FDA orphan designation status, will hopefully open ways to improve the quality of life of multiple myeloma patients.”

OWC, in collaboration with a medical center affiliated with Tel Aviv University, has tested several combinations of tetrahydrocannabinol (THC) and cannabidiol (CBD), as well as pure formulations of these compounds (50 percent concentration) extracted from cannabis. Experimental in vitro studies have shown that these cannabis-based compounds could induce multiple myeloma cell death by 60 percent.

OWC is developing a new delivery system in the form of a cannabis dissoluble tablet to treat multiple myeloma. This will give clinicians the chance to control and administer optimal dosages, overcoming one of the major disadvantages of smoking medical cannabis, as pointed out by physicians and researchers worldwide. This will also reduce possible pulmonary and lung-related side effects, said the company.

Before joining OWC, Baruch headed the Israeli Health Ministry’s Medical Marijuana Program from 2003 through 2013. There, he spearheaded efforts on regulation, chaired the indication committee, secured Helsinki Approvals for medical research, and managed regulation of patient licensing and dosage. He has extensive experience in researching medical cannabis, most notably for its effect on PTSD.



  1. Cannabis Oil says:

    Thank you for writing this awesome article. I’m a long time reader but I’ve
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  2. Donna says:

    I was just diagnosed 11/28/2017, on 11/30/2017 I started myself on 4 drops twice a day of 500 mg CBC oil. I’m keeping a journal. I’m wondering if I should take more, or less? Please feel free to reply with suggestions. Peace 🙂

  3. Sherry Wilson says:

    My fiance was diagnosed on December 12th with Multiple Myeloma. And we got the cbd oil but I know that alone will not kill the cancer we need the other half of this treatment and I know it’s so expensive. Good luck to every one fighting this disease

  4. Will says:

    My dad was diagnosed with MM in 2007. After a bone marrow transplant, his levels were almost undetectable. It came back again in 2010, where we proceeded with another transplant. After getting pneumonia in DEC 2017, it was determined that the MM was back. We found out 2 days ago that the current treatment isn’t having the intended success, and his body is too weak for another transplant. My nephew has had success with CBD treating his epilepsy.

    Please share if anyone is experiencing any success with it!

  5. Diagnosed stage 3 MM and received a course of C vamp Chemo and after getting ONJ ceased all Cancer treatment and not had a stem cell transplant, Ceased treatment in 2005 and I am the Longest patient in remission of all Cancer types in the Hospital treating me, I believe my use of Cannabis has helped with my many ailments which include Crohn’s, COPD, Chronic heart failure, stage 3 kidney disease and I take NO Pain relieve pharma Meds.

    • Sanet Jacobs says:

      Hi Clive, I’m also diagnosed in October 2018 with CLL Chronic Lymphocytic Leucemia and MM Multiple Myeloma. My numbers worsened & I do not want to go for Chemo. Rather think about using Cannabis together with a healthy diet & lifestyle. Do you also find that Cannabis helps you?

    • Andra Abolins says:

      Dear Clive, thank you for sharing & sincere congratulations on the success that you have had using cannabis. My dad (79) was diagnosed with MM in Oct 2016 and has been working his way through the various chemo options (velcade, revlamid, kyprolis) but he continues to relapse and his kidneys and heart have been compromised in the process. Wondering what dose of cannabis you are taking and in what form (oil, edibles?) and from what source as I know that not all cannabis is created equal. We live in Canada where cannabis is legal so we have many options available just not enough guidance.

  6. Anne kiraly says:

    Anne Kiraly my husband was diagnosed with multiple myeloma June 2019 to start chemo this week we were disappointed that it took 3 years to diagnose, seems to be catching every bug going around quite ill Where do we get cannabis oil

  7. Joan Fischer says:

    My husband was just diagnosed with MM, and had his bone marrow biopsy today.
    We do not have a recommendation on treatment yet, but we have Kaiser (HMO) and they cannot prescribe canabis. They are all for it, but I don’t know what to get. H is in a lot of pain as the kidney tumor ha metastasized into his spine/bones.
    Any recommendations on what to ask for is so appreciated.

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