A rabbit virus slowed the growth of multiple myeloma in mice, and eradicated the cancer in a fourth of the animals, a study reported. But researchers cautioned that the road to using the virus in humans would be long and uncertain. An advantage that a virus would have over chemotherapy…
Patients undergoing hematopoietic (donor) stem cell transplants could benefit from treatment with the experimental drug letermovir, which prevents the common viral infection cytomegalovirus (CMV). These results may help improve the safety of stem cell transplants with fewer side effects. The findings were presented at the 2017 Bone Marrow Transplant Tandem Meetings…
One kind of immune cell helps another stay active for years against invaders, a finding that could lead to therapies for autoimmune diseases and certain kinds of cancer, according to a study. The discovery that T-cells regulate plasma cells could provide insight into how some plasma cells become faulty, contributing…
The U.S. Food and Drug Administration has approved the anti-CD20 therapy Revlimid (lenalidomide) as a maintenance therapy for multiple myeloma patients who received an autologous hematopoietic stem cell transplant (auto-HSCT). Revlimid, which extended the time to disease progression and survival in years compared to placebo, is now the only…
Multiple myeloma (MM) patients treated at facilities that handle more patients may have better survival rates than those treated at lower-volume facilities, according to recent research. The study, “Association Between Treatment Facility Volume and Mortality of Patients With Multiple Myeloma,” was published in the Journal of Clinical Oncology. Multiple…
The first multiple myeloma patient has enrolled in a trial of Celyad‘s T-cell therapy for seven types of cancer that have failed to respond to treatment. It marks the first time a person with a blood cancer has enrolled in the Phase 1b THINK trial (NCT03018405), which will assess NKR-2…
A man who calls himself a Hollyweed artist has started an Indiegogo crowdfunding campaign to create T-shirts marking California’s legalization of recreational marijuana — and will donate some of the proceeds to the Institute of Multiple Myeloma. Matt Finegood is already selling shirts with an image of the famous Hollywood…
Patients with smoldering multiple myeloma (SMM), an asymptomatic form of myeloma, do not benefit from treatment with the anti-ICAM1 antibody BI-505, according to the results of a Phase 2 trial. But the drug is safe, with minimal long-term side effects, and researchers say it warrants further testing in other clinical…
A Phase 1 trial will soon be assessing Actimab-M, an anti-CD33 antibody bound to a radioactive compound, in heavily treated multiple myeloma patients, the compound’s developer, Actinium Pharmaceuticals, announced. Actimab-M is the CD33 targeting antibody, HuM-195, linked to the radioactive compound actinium 225. CD33 is a protein found in normal blood cells…
People with chronic diseases value the Affordable Care Act (ACA), commonly known as Obamacare, more than Americans in general, a survey by PatientsLikeMe has found. They are also less likely to want Obamacare repealed, claiming that the ACA needs only minor modifications to improve it. Expanding coverage for pre-existing conditions, holding insurance companies accountable,…
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